Read our 2025 publications below.
Novel regulators of heparan sulfate proteoglycans modulate cellular uptake of α-synuclein fibrils
October 2025
Benoît Vanderperre, Amitha Muraleedharan, Marie-France Dorion, Frédérique Larroquette, Esther Del Cid Pellitero, Nishani Rajakulendran, Carol X.-Q. Chen, Roxanne Larivière, Charlotte Michaud-Tardif, Thomas Goiran, Rony Chidiac, Damien Lipuma, Graham MacLeod, Rhalena Thomas, Zhangjie Wang, Wolfgang E. Reintsch, Wen Luo, Irina Shlaifer, Fuming Zhang, Ke Xia, Zachary Steinhart, Robert J. Linhardt, Jean-François Trempe, Jian Liu, Thomas M. Durcan, Stephane Angers & Edward A. Fon
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Pro-Inflammatory Molecules Implicated in Multiple Sclerosis Divert the Development of Human Oligodendrocyte Lineage Cells
July 2025
Gabriela J Blaszczyk, Abdulshakour Mohammadnia, Valerio E C Piscopo, Julien Sirois, Qiao-Ling Cui, Moein Yaqubi, Thomas M Durcan, Raphael Schneider, Jack P Antel​
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DOI: 10.1212/NXI.0000000000200407
BetaII-Spectrin Gaps and Patches Emerge from the Patterned Assembly of the Actin/Spectrin Membrane Skeleton in Human Motor Neuron Axons
September 2025
Nahir Guadalupe Gazal, Maria Jose Castellanos-Montiel, Guillermina Bruno, Anna Kristina Franco-Flores, Sarah Lépine, Lale Gursu, Ghazal Haghi, Gilles Maussion, Agustín Anastasía, Mariano Bisbal, Ezequiel Axel Gorostiza, Thomas M Durcan, Nicolás Unsain
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Evaluation of Additive Neuroprotective Effect of Combination Therapy for Parkinson's Disease Using In Vitro Models
March 2025
Alexander Shtilbans, Elise Esneault, Florian Simon, Joseph R Mazzulli, Drew J Quiriconi, Dror Rom, Wolfgang E Reintsch, Andrea I Krahn, Thomas M Durcan​
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DOI: 10.3390/antiox14040396
Transcriptome-based screening in TARDBP/TDP-43 knock-in motor neurons identifies the NEDD8-activating enzyme inhibitor MLN4924
August 2025
Sarah Lépine, Gilles Maussion, Alexandria Schneider, Angela Nauleau-Javaudin, María José Castellanos-Montiel, Georgina Jiménez Ambriz, Dan Spiegelman, Narges Abdian, Anna Krystina Franco-Flores, Ghazal Haghi, Lale Gursu, Michael R. Fiorini, Allison A. Dilliott, Sali M. K. Farhan, Mathilde Chaineau & Thomas M. Durcan
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Single cell RNA-seq to identify subpopulations of glial progenitors iniPSC-derived oligodendroglial lineage cultures
April 2025
Gabriela J. Blaszczyk, Valerio E. C. Piscopo, Taylor M. Goldsmith, Alexandra Chapleau, Julien Sirois, Geneviève Bernard, Jack P. Antel & Thomas M. Durcan
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