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🎥 New Video Spotlight!
Watch the video to see the research of Valerio Piscopo, Gabriela Blaszczyk, Taylor Goldsmith, and colleagues as they explore glial heterogeneity in iPSC-derived oligodendrocytes.
Their work reveals distinct glial subpopulations and offers a new tool to study glial development at the transcriptomic level.
📃 To read the full article click here: https://lnkd.in/ePPfzyk2
#Neuroscience #iPSC #GlialCells #StemCellResearch #Oligodendrocytes
#BiomedicalResearch

🧫 Cell of the Week: Human Oligodendrocyte Progenitor Cells (OPCs)
After 75 days of differentiation from human induced pluripotent stem cells, following the protocol in Piscopo et al., 2024, we successfully generated oligodendrocyte progenitor cells (OPCs). These cells were then cultured on poly-L-lactide microfiber plates featuring 2 µm-thick filaments designed to mimic neuronal axons.
To assess maturation, cells were fixed and immunolabeled for key oligodendrocyte markers: O4 (green) and MBP (red). Imaging was performed using a Live Cell Scope fluorescence microscope (Zeiss). The final image was color-enhanced to emphasize structural elements: microfibers appear in magenta, O4-positive cells in green, and MBP expression in red.
Proud to share this visual snapshot of human oligodendrocyte development in action! 🔬 🧠

#Oligodendrocytes #iPSC #Neuroscience #Microscopy #Filaments

Photo credits: Valerio Piscopo

This calcium imaging video shows spontaneous firing in a 3D motor neuron spheroid, visualized using the Opera Phenix system. Each burst of fluorescence represents neural activity, activity that fades in ALS as motor neurons degenerate.
June is ALS Awareness Month🌹. Behind every image like this is a patient, a family, and a fight for answers. Sharing this not just for the science, but for the hope it represents 💜 .

#ALSawareness #CalciumImaging #Neuroscience #HighContentImaging #ALSresearch #EndALS

Video credits: Mathilde Chaineau and Vincent Soubannier

Inside a Microelectrode Array (MEA) palate: The MEA contains a grid of tiny electrodes embedded in the bottom of each well, designed to detect and record electrical signals from cultured cells such as neurons. These signals reflect the cells electrical activity, allowing us to study network behavior in real time. Have you ever used a plate like this? #MEA #Neuroscience #iPSC #research

We are kicking off summer with hands-on training for our new students. This video is just a glimpse! Stay tuned for our next posts where we officially introduce our amazing 2025 summer student cohort! 👩🏻‍🔬👨🏻‍🔬#summerstudents #training #neuroscience #cellculture #ipsc

What do you do to keep busy while waiting during experiments? 😅🧪

Credits: Taylor Goldsmith, Doris Hua and Anna Franco
#neuroscience #relatable #lab #funny #experiments

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Read about the latest updates happening at the EDDU from our Linkedin

The EDDU is also on Instagram! Check out our latest posts below.

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