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Read about the latest updates happening at the EDDU

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Image of iPSC-derived motor neurons

By Mathilde Chaineau


Read the EDDU's monthly newsletter to learn more about the latest events and achievements happening at the EDDU!

Click here to read the February 2023 newsletter.

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Publication Updates


An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids

February 2023

Maria Jose Castellanos-Montiel et al. 

DOI: 10.3390/cells12040545


Rapid macropinocytic transfer of α-synuclein to lysosomes

July 2022

Armin Bayati et al. 

DOI: 10.1016/j.celrep.2022.111102

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Systematic comparison of culture media uncovers phenotypic shift of primary human microglia defined by reduced reliance to CSF1R signaling

January 2023

Marie-France Dorion et al.

DOI: 10.1002/glia.24338


Generation of homozygous PRKN, PINK1 and double PINK1/PRKN knockout cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing

May 2022

Carol X.-Q. Chen et al. 

DOI: 10.1016/j.scr.2022.102806

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Generation of patient-derived pluripotent stem cell-lines and CRISPR modified isogenic controls with mutations in the Parkinson’s associated GBA gene

October 2022

Carol X.-Q. Chen  et al. 

DOI: 10.1016/j.scr.2022.102919


TDP-43 dysregulation and neuromuscular junction disruption in amyotrophic lateral sclerosis

December 2022

Sarah Lépine et al.


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