Read our publications and view the posters and presentations we have shared at scientific meetings. For inquiries regarding our publications, please email us.

Most Recent Publications
See the drop down menu under Publications for yearly archives.

MerTK is a mediator of alpha-synuclein fibril uptake by human microglia

September 2023

Dorion M. et al.

https://doi.org/10.1093/brain/awad298

Image that represents the paper: Excitatory neuron-specific suppression of the integrated stress response pathway contributes to autism-related phenotypes in a mouse model of fragile X syndrome

Excitatory neuron-specific suppression of the integrated stress response pathway contributes to autism-related phenotypes in a mouse model of fragile X syndrome

April 2023

Hooshmandi M et al.

DOI: 10.1101/2023.04.24.538123

Structure-based design and characterization of Parkin-activating mutations

March 2023

Micheal Stevens et al.

DOI: 10.26508/lsa.202201419

An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids

February 2023

Maria Jose Castellanos-Montiel et al.

DOI: 10.3390/cells12040545

Image that represents the paper: Fast 3D Optoacoustic Mesoscopy of Neuromelanin Through Entire Human Midbrain Organoids at Single-Cell Resolution

Fast 3D Optoacoustic Mesoscopy of Neuromelanin Through Entire Human Midbrain Organoids at Single-Cell Resolution

July 2023

Englert L. et al.

DOI: 10.1002/lpor.202300443

α-synuclein preformed fibrils bind to β-neurexins and impair β-neurexin-mediated presynaptic organization

April 2023

Benjamin Feller et al.

DOI: 10.1101/2023.01.28.526024

Visualization of α-synuclein trafficking via nanogold labeling and electron microscopy

February 2023

Armin Bayati et al.

DOI: 10.1016/j.xpro.2023.102113

Image that represents the paper: Systematic comparison of culture media uncovers phenotypic shift of primary human microglia defined by reduced reliance to CSF1R signaling

Systematic comparison of culture media uncovers phenotypic shift of primary human microglia defined by reduced reliance to CSF1R signaling

January 2023

Marie-France Dorion et al.

DOI: 10.1002/glia.24338

Image of Cortical Neurons 7 weeks FB media 2 bar

The next generation of tools and technologies for studying human neurons in a dish

April 2023

Durcan TM, Axtman AD.

DOI: 10.3389/fncel.2023.1196543

Compressive molding of engineered tissues via thermoresponsive hydrogel devices

March 2023

Cassel de Camps C, Mok S, Ashby E, Li C, Lépine P, Durcan TM, Moraes C.

DOI: 10.1039/d3lc00007a

Image that represents the paper: Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

February 2023

Philip McGoldrick et al.

DOI: 10.1101/2021.10.20.465148

Posters

Image that represents the paper: Single-cell RNA sequence analysis of post-mortem midbrain tissue reveals altered glial cell function in Parkinson's disease

Single-cell RNA sequence analysis of post-mortem midbrain tissue reveals altered glial cell function in Parkinson's disease

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Indra Roy, Rhalena A. Thomas, Thomas M. Durcan

The Mer tyrosine kinase mediates the internalization of alpha-synuclein fibrils by human microglia

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Marie-France Dorion, Konstantin Senkevich, Moein Yaqubi, Wen Luo, Amber Wallis, Irina Shlaifer, Jack P. Antel, Ziv Gan-Or, Tim Bartel, Thomas M. Durvan, Luke M. Healy

Screening for compounds that reduce alpha synuclein fibril load in iPSC-derived neuronal cells

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Andrea I. Krahn, Wolfgang E. Reintsch, Chanshuai Han, Emmanuelle Nguyen-Renou, Carol X.-Q. Chen, Wen Luo, Edward A. Fon, Thomas M. Durcan

Presentations

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Read our publications and view the posters and presentations we have shared at scientific meetings. For inquiries regarding our publications, please email us.

Most Recent Publications See the drop down menu under Publications for yearly archives.

MerTK is a mediator of alpha-synuclein fibril uptake by human microglia

Excitatory neuron-specific suppression of the integrated stress response pathway contributes to autism-related phenotypes in a mouse model of fragile X syndrome

Structure-based design and characterization of Parkin-activating mutations

An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids

Fast 3D Optoacoustic Mesoscopy of Neuromelanin Through Entire Human Midbrain Organoids at Single-Cell Resolution

α-synuclein preformed fibrils bind to β-neurexins and impair β-neurexin-mediated presynaptic organization

Visualization of α-synuclein trafficking via nanogold labeling and electron microscopy

Systematic comparison of culture media uncovers phenotypic shift of primary human microglia defined by reduced reliance to CSF1R signaling

The next generation of tools and technologies for studying human neurons in a dish

Compressive molding of engineered tissues via thermoresponsive hydrogel devices

Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

Posters

Single-cell RNA sequence analysis of post-mortem midbrain tissue reveals altered glial cell function in Parkinson's disease

The Mer tyrosine kinase mediates the internalization of alpha-synuclein fibrils by human microglia

Screening for compounds that reduce alpha synuclein fibril load in iPSC-derived neuronal cells

Presentations

Most Recent Publications
See the drop down menu under Publications for yearly archives.