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Read our publications and view the posters and presentations we have shared at scientific meetings. For inquiries regarding our publications, please email us. 

Most Recent Publications
See the drop down menu under Publications for yearly archives.

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Systematic comparison of culture media uncovers phenotypic shift of primary human microglia defined by reduced reliance to CSF1R signaling

January 2023

Marie-France Dorion et al.

DOI: 10.1002/glia.24338


Rapid macropinocytic transfer of α-synuclein to lysosomes

July 2022

Armin Bayati et al. 

DOI: 10.1016/j.celrep.2022.111102


TDP-43 dysregulation and neuromuscular junction disruption in amyotrophic lateral sclerosis

December 2022

Sarah Lépine et al.

DOI: 10.1186/s40035-022-00331-z


Generation of homozygous PRKN, PINK1 and double PINK1/PRKN knockout cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing

May 2022

Carol X.-Q. Chen et al. 

DOI: 10.1016/j.scr.2022.102806

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Generation of patient-derived pluripotent stem cell-lines and CRISPR modified isogenic controls with mutations in the Parkinson’s associated GBA gene

October 2022

Carol X.-Q. Chen  et al. 

DOI: 10.1016/j.scr.2022.102919


A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease

March 2022

Morgan Bérard et al. 

DOI: 10.1371/journal.pbio.3001578


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A convolutional neural network distinguishing between Parkinson's disease and healthy cells using microscopy images

Eddie Cai, Wolfgang Reintsch, Chanshaui Han, Sneha Shinde, Roxanne Larivière, Andrea Krahn, Carol X.Q. Chen, Emmanualle Nguyen-Renou, Anna Franco-Flores, Thomas M. Durcan, Edward A. Fon, Rhalena A. Thomas

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Quantitative characterization of variability in cortical neurons between healthy human induced pluripotent stem cell lines

Carol X-Q. Chen, Narges Abdian, Rhalena A. Thomas, Eddie Cai, Edward A. Fon, Thomas M. Durcan, Gracia Gu

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Standardized QC workflow foranalyzing the quality and differentiation potential of human iPSCs

 Carol X-Q. Chen, Narges Abdian, Gilles Maussion, Rhalena A. Thomas, Iveta Demirova, Eddie Cai, Edward A. Fon, Thomas M. Durcan

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Characterization of the activity-dependent development of iPSC-derived neurons from Fragile X patients

Gilles Maussion, Cecilia Rocha, Vincent Soubannier, Thomas M. Durcan


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