Read our publications and view the posters and presentations we have shared at scientific meetings. For inquiries regarding our publications, please email us.

Most Recent Publications
See the drop down menu under Publications for yearly archives.

Single cell RNA-seq to identify subpopulations of glial progenitors in iPSC-derived oligodendroglial lineage cultures

April 2025

Gabriela J. Blaszczyk et al.

https://doi.org/10.1038/s41540-025-00515-z

Early nuclear phenotypes and reactive transformation in human iPSC-derived astrocytes from ALS patients with SOD1 mutations

August 2024

Vincent Soubannier et al.

https://doi.org/10.1002/glia.24598

Illumination of understudied ciliary kinases

March 2024

Flax R. et al.

https://doi.org/10.1186/s13041-024-01088-4

Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons

March 2024

Lépine S. et al.

https://doi.org/10.1016/j.isci.2024.109166

An Inducible Luminescent System to Explore Parkinson’s Disease-Associated Genes

August 2024

Anelya Gandy et al.

https://doi.org/10.3390/ijms25179493

Generation of human iPSC-derived phrenic-like motor neurons to model respiratory motor neuron degeneration in ALS

February 2024

Thiry L. et al.

https://doi.org/10.1002/glia.24524

The 37TrillionCells initiative for improving global healthcare via cell-based interception and precision medicine: focus on neurodegenerative diseases

April 2024

Coulombe B. et al.

https://doi.org/10.1186/s13041-024-01088-4

CelltypeR: A flow cytometry pipeline to characterize single cells from brain organoids

July 2024

Rhalena A. Thomas et al.

https://doi.org/10.1016/j.isci.2024.110613

An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders

April 2024

Dorion M. et al.

https://doi.org/10.1186/s13024-024-00723-x

The Use of a SOX10 Reporter Towards Ameliorating Oligodendrocyte Lineage Differentiation from Human Induced Pluripotent Stem Cells

March 2024

Piscopo V. et al.

https://doi.org/10.1002/glia.24524

Posters

Development of in vitro ALS discovery and
translational assays with patient-derived cells

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Mathilde Chaineau, Vincent Soubannier, Lale Gursu, Anna Krystina Franco-Flores, Ghazal Haghi, María José Castellanos-Montiel
Sarah Lépine, Carol X-Q Chen, Valerio Piscopo, Narges Abdian and Thomas M. Durcan

Studying the effects of NF subunit abnormalities in neuromuscular junction morphology and function

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María José Castellanos-Montiel, Anna Krystina Franco-Flores, Sarah Lépine, Lale Gursu, Ghazal Haghi, Mathilde Chaineau, Carol X-Q Chen, Narges Abdian, Eric Deneault, Michael Nicouleau, Thomas M. Durcan

Screening for compounds that reduce alpha synuclein fibril load in iPSC-derived neuronal cells

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Andrea I. Krahn, Wolfgang E. Reintsch, Chanshuai Han, Emmanuelle Nguyen-Renou, Carol X.-Q. Chen, Wen Luo, Edward A. Fon, Thomas M. Durcan

Nuclear phenotypes and astrogliosis in astrocytes derived from ALS SOD1(A4V)-mutated iPSCs

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Vincent Soubannier, Mathilde Chaineau, Lale Gursu, Sarah Lepine, Guy Rouleau, Thomas M. Durcan and Stefano Stifani

Image that represents the poster: Single-cell RNA sequence analysis of post-mortem midbrain tissue reveals altered glial cell function in Parkinson's disease

Single-cell RNA sequence analysis of post-mortem midbrain tissue reveals altered glial cell function in Parkinson's disease

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Indra Roy, Rhalena A. Thomas, Thomas M. Durcan

Transcriptome-based in silico screening in human motor neurons with ALS-associated mutations in TARDBP/TDP-43

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Sarah Lépine, Gilles Maussion, Alexandria Schneider, Angela Nauleau-Javaudin, Georgina Jiménez Ambriz, Dan Spiegelman, María José Castellanos-Montiel, Narges Abdian, Anna K.Franco-Flores, Ghazal Haghi, Lale Gursu, Mathilde Chaineau, and Thomas M. Durcan

The Mer tyrosine kinase mediates the internalization of alpha-synuclein fibrils by human microglia

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Marie-France Dorion, Konstantin Senkevich, Moein Yaqubi, Wen Luo, Amber Wallis, Irina Shlaifer, Jack P. Antel, Ziv Gan-Or, Tim Bartel, Thomas M. Durvan, Luke M. Healy

Presentations

Image of Thomas Durcan presentation about iPSC

Presentations

Read our publications and view the posters and presentations we have shared at scientific meetings. For inquiries regarding our publications, please email us.

Most Recent Publications See the drop down menu under Publications for yearly archives.

Single cell RNA-seq to identify subpopulations of glial progenitors in iPSC-derived oligodendroglial lineage cultures

Early nuclear phenotypes and reactive transformation in human iPSC-derived astrocytes from ALS patients with SOD1 mutations

Illumination of understudied ciliary kinases

Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons

An Inducible Luminescent System to Explore Parkinson’s Disease-Associated Genes

Generation of human iPSC-derived phrenic-like motor neurons to model respiratory motor neuron degeneration in ALS

The 37TrillionCells initiative for improving global healthcare via cell-based interception and precision medicine: focus on neurodegenerative diseases

CelltypeR: A flow cytometry pipeline to characterize single cells from brain organoids

An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders

The Use of a SOX10 Reporter Towards Ameliorating Oligodendrocyte Lineage Differentiation from Human Induced Pluripotent Stem Cells

Posters

Development of in vitro ALS discovery and translational assays with patient-derived cells

Studying the effects of NF subunit abnormalities in neuromuscular junction morphology and function

Screening for compounds that reduce alpha synuclein fibril load in iPSC-derived neuronal cells

Nuclear phenotypes and astrogliosis in astrocytes derived from ALS SOD1(A4V)-mutated iPSCs

Single-cell RNA sequence analysis of post-mortem midbrain tissue reveals altered glial cell function in Parkinson's disease

Transcriptome-based in silico screening in human motor neurons with ALS-associated mutations in TARDBP/TDP-43

The Mer tyrosine kinase mediates the internalization of alpha-synuclein fibrils by human microglia

Presentations

Most Recent Publications
See the drop down menu under Publications for yearly archives.

Development of in vitro ALS discovery and
translational assays with patient-derived cells